Psychometric properties of the Friedreich Ataxia Rating Scale

Christian Rummey, Louise A. Corben, Martin B. Delatycki, S.H. Subramony, Khalaf Bushara, Christopher M. Gomez, Joseph Chad Hoyle, Grace Yoon, Bernard Ravina, Katherine D. Mathews, George Wilmot, Theresa Zesiewicz, Susan Perlman, Jennifer M. Farmer, David R. Lynch; Neurol Genet Dec 2019, 5 (6) 371; DOI: 10.1212/NXG.0000000000000371

A correlation-based psychometric analysis of the neurologic FARSn score justifies the overall validity of the scale. In addition, omission of items of limited functional significance as created in the mFARS improves the features of the measures. Such information is crucial to the ongoing application of the mFARS in natural history studies and clinical trials. Additional analyses of longitudinal changes will be necessary to fully ascertain its utility, especially in nonambulant patients.

Psychometric properties of the Friedreich Ataxia Rating Scale