Identification of Frataxin as a regulator of ferroptosis

Jing Du, Yi Zhou, Yanchun Li, Jun Xia, Yongjian Chen, Sufeng Chen, Xin Wang, Weidong Sun, Tongtong Wang, Xueying Ren, Xu Wang, Yihan An, Kang Lu, Wanye Hu, Siyuan Huang, Jianghui Li, Xiangmin Tong, Ying Wang; Redox Biology, 2020, 101483, doi:10.1016/j.redox.2020.101483.

This paper suggests that FXN is a novel ferroptosis modulator, as well as a potential provided target to improve the antitumor activity based on ferroptosis.


Identification of Frataxin as a regulator of ferroptosis