This review focuses on the use of nanosystems as an encouraging therapeutic approach targeting molecular pathways involved in localized and systematic neurodegenerative diseases. Among this latter, Friedreich's ataxia is an untreatable complex multisystemic disorder and the most spread type of ataxia, that represents a test case to validate the clinical potential of therapeutic strategies based on nanoparticles with pleiotropic effects.
Saturday, February 4, 2023
Multifaceted nanoparticles: emerging mechanisms and therapies in neurodegenerative diseases
Mistretta, M., Farini, A., Torrente, Y., & Villa, C. (2023). Brain : a journal of neurology, awad014. Advance online publication. doi:10.1093/brain/awad014
