We conclude that ketone metabolism is essential for the development of the somatosensory nervous system. These findings also suggest that decreased ketone oxidation in the somatosensory nervous system may explain the neurological symptoms of Friedreich's ataxia.
Wednesday, May 3, 2023
Ketolysis is required for the proper development and function of the somatosensory nervous system
Enders J, Jack J, Thomas S, Lynch P, Lasnier S, Cao X, Swanson MT, Ryals JM, Thyfault JP, Puchalska P, Crawford PA, Wright DE. Ketolysis is required for the proper development and function of the somatosensory nervous system. Exp Neurol. 2023 Apr 24:114428. doi: 10.1016/j.expneurol.2023.114428. Epub ahead of print. PMID: 37100111.
