Patient-Derived iPSC-Neurons and Microglia for Modeling Friedreich’s Ataxia Disease

1694 Patient-Derived iPSC-Neurons and Microglia for Modeling Friedreich’s Ataxia Disease; Priyanka Mishra, Anusha Sivakumar, Avalon Johnson, Emily Hansen, Jacqueline Nguyen, Nicole Coufal, Stephanie Cherqui. May 01, 2023 Volume 31 Issue 4 Supplement 1 S1-794 26th Annual Meeting of the American Society of Gene & Cell Therapy.

Utilising these two models, to understand the role of microglia in the neurodegeneration in FRDA, and its rescue by the gene corrected microglia.

Patient-Derived iPSC-Neurons and Microglia for Modeling Friedreich’s Ataxia Disease