Therapeutic Delivery Of A Gene To Dysfunctional Nerves

Therapeutic Delivery Of A Gene To Dysfunctional Nerves

ScienceDaily (June 15, 2009) — In many sensory neuronopathies, painful conditions affecting sensory nerves outside the brain and spinal cord, the affected nerves are in a region known as the DRG. These conditions are difficult to treat. However, researchers have now developed an approach to target therapeutic genes to DRG nerves, and used it to reduce sensory nerve dysfunction in a mouse model of Sandhoff disease, an inherited condition in which many nerves, including those in the DRG, are affected.

Full Text http://www.sciencedaily.com/releases/2009/06/090615171509.htm

Keywords: sensory neuronopathies, painful , DRG, therapeutic genes , dorsal root ganglion , adenoviruses, mice.