Wednesday, October 20, 2010

Pharmacokinetic evaluation of idebenone.

Expert Opin Drug Metab Toxicol. 2010 Nov;6(11):1437-44.

Becker C, Bray-French K, Drewe J.
Basel Pharmacoepidemiology Unit, University Hospital Basel, Switzerland.

Conclusions: Idebenone shows dose-proportional pharmacokinetics in healthy subjects in daily doses up to 2250 mg, and was safe and well tolerated at doses up to 2250 mg/day, in clinical studies.

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