The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy

Arnulf H. Koeppen, Alyssa B. Becker, Paul J. Feustel, Benjamin B. Gelman, Joseph E. Mazurkiewicz. Journal of the Neurological Sciences, Available online 4 June 2016, ISSN 0022-510X, doi: 10.1016/j.jns.2016.06.006.

Highlights
-The most frequent cause of death in Friedreich ataxia is cardiomyopathy
-Abnormal intercalated discs contribute to Friedreich cardiomyopathy
-Intercalated discs and gap junctions are normal in long-surviving patients

 The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy