Health related quality of life in Friedreich Ataxia in a large heterogeneous cohort

Emily Xiong, Abigail E. Lynch, Louise A. Corben, Martin B. Delatycki, S.H. Subramony, Khalaf Bushara, Christopher M. Gomez, J. Chad Hoyle, Grace Yoon, Bernard Ravina, Katherine D. Mathews, George Wilmot, Theresa Zesiewicz, M. Susan Perlman, Jennifer M. Farmer, Christian Rummey, David R. Lynch; Neurological Sciences, Volume 0, Issue 0, 116642 DOI:10.1016/j.jns.2019.116642

The SF-36 and symptom specific scales capture dysfunction in FRDA in a manner that reflects disease status. HRQOL dysfunction was greatest on physically related scales; such scales correlated with disease duration, indicating that they worsen with progressing disease.

Health related quality of life in Friedreich Ataxia in a large heterogeneous cohort