Analyses of statistical properties of SARA suggest a variable sensitivity of the scale at different disease stages, and provide important information for population selection and result interpretation in future clinical trials.
Tuesday, August 29, 2023
Longitudinal changes of SARA scale in Friedreich ataxia: Strong influence of baseline score and age at onset
Porcu, L., Fichera, M., Nanetti, L., Rulli, E., Giunti, P., Parkinson, M.H., Durr, A., Ewenczyk, C., Boesch, S., Nachbauer, W., Indelicato, E., Klopstock, T., Stendel, C., Rodríguez de Rivera, F.J., Schöls, L., Fleszar, Z., Giordano, I., Didszun, C., Castaldo, A., Rai, M., Klockgether, T., Pandolfo, M., Schulz, J.B., Reetz, K., Mariotti, C. and (2023), Longitudinal changes of SARA scale in Friedreich ataxia: Strong influence of baseline score and age at onset. Ann Clin Transl Neurol. doi:10.1002/acn3.51886