We believe that repeat-caused replication attenuation in vivo is due to triplex formation. The apparent link between the replication stalling and length polymorphism of the repeat points to a new model for the repeat expansion.
Thursday, August 31, 2023
Replication Stalling at Friedreich's Ataxia (GAA)n Repeats In Vivo
Maria M. Krasilnikova & Sergei M. Mirkin (2004) Replication Stalling at Friedreich's Ataxia (GAA)n Repeats In Vivo, Molecular and Cellular Biology, 24:6, 2286-2295, DOI: 10.1128/MCB.24.6.2286-2295.2004
