In this review, we delve into recent insights further defining the relationship between mitochondrial Ca2+ dynamics and oxidative phosphorylation. Our focus is on how such regulation affects cardiac function in health and disease, including heart failure, ischemia-reperfusion, arrhythmias, catecholaminergic polymorphic ventricular tachycardia, mitochondrial cardiomyopathies, Barth syndrome, and Friedreich's ataxia.
Monday, June 3, 2024
Mitochondrial calcium regulation of cardiac metabolism in health and disease
Balderas E, Lee SH, Rai NK, et al. Mitochondrial calcium regulation of cardiac metabolism in health and disease. Physiology (Bethesda, Md.). 2024 May. DOI: 10.1152/physiol.00014.2024. PMID: 38713090.
