Functional Protein Delivery into Neurons Using Polymeric Nanoparticles

Originally published In Press as doi:10.1074/jbc.M805956200 on January 7, 2009
J. Biol. Chem., Vol. 284, Issue 11, 6972-6981, March 13, 2009

Functional Protein Delivery into Neurons Using Polymeric Nanoparticles*

Linda Hasadsri, Jörg Kreuter, Hiroaki Hattori¶, Tadao Iwasaki¶, and Julia M. George1
From the Department of Cell and Developmental Biology and College of Medicine (Medical Scholars Program), University of Illinois Urbana-Champaign, Urbana, Illinois 61801, the Institut für Pharmazeutische Technologie, Biozentrum, Johann Wolfgang Goethe Universität, Frankfurt D-60439, Germany, the ¶Department of Advanced Medical Technology and Development, BML, Inc., 1361-1 Matoba, Kawagoe, Saitama 350-1101, Japan, and the Department of Molecular and Integrative Physiology, University of Illinois Urbana-Champaign, Urbana, Illinois 61801

The on-line version of this article (available at http://www.jbc.org) contains supplemental Figs. S1–S5.

1 To whom correspondence should be addressed: Dept. of Molecular and Integrative Physiology, 524 Burrill Hall, 407 S. Goodwin Ave, Urbana, IL 61801. Tel.: 217-244-4525; Fax: 217-333-1133; E-mail: j-george@illinois.edu.