Estrogen Protection in Friedreich's Ataxia Skin Fibroblasts

Endocrinology, doi:10.1210/en.2011-0184, published online on May 3, 2011

Timothy E. Richardson, Shao-Hua Yang, Yi Wen and James W. Simpkins

Institute for Aging and Alzheimer's Disease Research, Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, Texas 76107

Keywords: Estrogens, neurodegenerative diseases, 17β-estradiol (E2), estrogen-like compounds, Friedreich's ataxia (FRDA), FRDA skin fibroblasts, estrogen receptor-α, estrogen receptor-β, G protein-coupled receptor 30, antioxidant properties, phenolic compounds, phenolic E2-like compounds.