The heart in Friedreich's Ataxia: Basic findings and clinical implications

Progress in Pediatric Cardiology - May 2011 (Vol. 31, Issue 2, Pages 103-109, DOI: 10.1016/j.ppedcard.2011.02.007)

R. Mark Payne

Riley Heart Research Center, Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, 46202, United States

Keywords: Friedreich's Ataxia, mitochondrial disease, frataxin, GAA triplet expansion, progressive neuropathy, hypertrophic cardiomyopathy, arrhythmias, heart failure, cardiovascular stress intolerance, histone deacetylase inhibitors, enzyme replacement.