Tuesday, May 12, 2009

A Study Investigating the Long-Term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia

A Study Investigating the Long-Term Safety and Efficacy of Deferiprone in Patients With Friedreich's Ataxia

http://www.clinicaltrials.gov/ct2/show/NCT00897221?term=friedreich

This study is not yet open for participant recruitment.
Verified by ApoPharma, May 2009
First Received: May 8, 2009 No Changes Posted
Sponsored by: ApoPharma

Information provided by: ApoPharma
ClinicalTrials.gov Identifier: NCT00897221

Practical guide to neurogenetics

http://www.thelancet.com/journals/laneur/article/PIIS147444220970122X/fulltext?rss=yes Practical guide to neurogenetics


Practical Guide to Neurogenetics
Thomas Warner, Simon HammansElsevier Saunders, 2008Pp 344. $65·95. ISBN-978-0750654104

Saturday, May 9, 2009

Exercise, PGC-1α, and metabolic adaptation in skeletal muscle

Appl. Physiol. Nutr. Metab. 34(3): 424–427 (2009) doi:10.1139/H09-030 Published by NRC Research Press / Publié par les Presses scientifiques du CNRC

Full text: http://article.pubs.nrc-cnrc.gc.ca/RPAS/rpv?hm=HInit&journal=apnm&volume=34&calyLang=eng&afpf=h09-030.pdf

Exercise, PGC-1α, and metabolic adaptation in skeletal muscle

Zhen Yan

Endurance exercise is protective for mice with mitochondrial myopathy

J Appl Physiol 106: 1712-1719, 2009. First published March 12, 2009; doi:10.1152/japplphysiol.91571.2008 8750-7587/09 $8.00

HIGHLIGHTED TOPIC Regulation of Protein Metabolism in Exercise and Recovery

Endurance exercise is protective for mice with mitochondrial myopathy

Tina Wenz,1 Francisca Diaz,1 Dayami Hernandez,1 and Carlos T. Moraes1,2
Departments of 1Neurology and of 2Cell Biology and Anatomy, University of Miami School of Medicine, Miami, Florida
Submitted 8 December 2008 ; accepted in final form 9 March 2009

Address for reprint requests and other correspondence: C. T. Moraes, Dept. of Neurology, Miller School of Medicine, Univ. of Miami, 1095 NW 14th Terrace, Miami, FL 33136 (e-mail: cmoraes@med.miami.edu

Thursday, May 7, 2009

p53/CEP-1 Increases or Decreases Lifespan, Depending on Level of Mitochondrial Bioenergetic Stress.

Aging Cell. 2009 Apr 22. [Epub ahead of print]

p53/CEP-1 Increases or Decreases Lifespan, Depending on Level of Mitochondrial Bioenergetic Stress.

Ventura N, Rea SL, Schiavi A, Torgovnick A, Testi R, Johnson TE.
Institute for Behavioral Genetics, University of Colorado at Boulder, Box 447, Boulder, CO 80309, USA.

Oxidative stress induces degradation of mitochondrial DNA

http://nar.oxfordjournals.org/cgi/content/short/37/8/2539?rss=1

http://nar.oxfordjournals.org/cgi/reprint/37/8/2539 (Full text)

Nucleic Acids Research Advance Access originally published online on March 5, 2009 Nucleic Acids Research 2009 37(8):2539-2548; doi:10.1093/nar/gkp100

Oxidative stress induces degradation of mitochondrial DNA

Inna Shokolenko, Natalia Venediktova, Alexandra Bochkareva, Glenn L. Wilson and Mikhail F. Alexeyev*
Department of Cell Biology and Neuroscience, University of South Alabama, Mobile, AL 36688, USA
*To whom correspondence should be addressed. Tel: +1 251 460 6789; Fax: +1 251 460 6771; Email: malexeye@jaguar1.usouthal.edu

Received September 4, 2008. Revised January 25, 2009. Accepted February 8, 2009.

Fly Study Suggests That Gene May 'Bypass' Disease-Linked Mitochondrial Defects

Fly Study Suggests That Gene May 'Bypass' Disease-Linked Mitochondrial Defects

Article Date: 06 May 2009 - 6:00 PDT
http://www.medicalnewstoday.com/articles/149070.php

Wednesday, May 6, 2009

Matching Supply and Demand

Science 24 April 2009:Vol. 324. no. 5926, p. 440DOI: 10.1126/science.324_440b
Editors' Choice: Highlights of the recent literature

http://www.sciencemag.org/cgi/content/full/324/5926/440-b?rss=1

Biochemistry:

Matching Supply and Demand

Valda Vinson

Nat. Struct. Mol. Biol. 16, 390 (2009).

Saturday, May 2, 2009

Dendrimers as synthetic gene vectors: Cell membrane attachment

J. Chem. Phys. 130, 155101 (2009); DOI:10.1063/1.3109902 Published 16 April 2009

N. K. Voulgarakis, K. Ø. Rasmussen, and P. M. Welch
Theoretical Division and Center for Nonlinear Studies, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, USA

Dendrimers as synthetic gene vectors: Cell membrane attachment






First Large-Scale Computer Simulation Of Gene Therapy

http://www.medicalnewstoday.com/articles/148319.php

First Large-Scale Computer Simulation Of Gene Therapy